| PROTAC (PROTEIN TARGETING CHIMERA) | Proteasome | POI and E3 |
| GLUE | Proteasome | POI and E3 |
| LYTAC (Lysosomal targeted chimera) | Lysosome (endosome) | POI and Lysosomal recruiter (M6RP) |
| ATTEC (Autophagosome tethering compounds) | Lysosome (autophagy) | POI and phagophore |
| HALOPROTAC | Proteasome | Halo-tagged fusion POI and VHL |
| AbTAC (Antibody based PROTAC) | Lysosome | Cell surface POI and membrane-bound E3 |
| RIBOTAC (ribonuclease targeting chimeras) | RNA degradation | RNA and RNAse |
| HEMTAC (HSP90 mediated targeting chimeras) | Proteasome | POI and HSP90 |
| RIPTAC (regulated induced targeting chimeras) | Targeted protein inhibition | oncoprotein and essential protein |
| AceTAG (acetylation targeting proteins) | PTM (acetylation) | lysine acetyltransferase and POI |
| PHICS (phosphorylation induced chimeras) | PTM (phosphorylation) | POI and kinase |
| PhosTAC (phosphorylation targeting chimeras) | PTM (dephosphorylation) | POI and phosphatase |
| DUBTAC (deubiquitinase targeting chimera) | Targeted protein stabilization | POI and Dub receptor |
| TF-DUBTAC | Targeted transcription factor stabilization | DNA and Dub |
| TRAFTAC (transcription factor targeting chimera) | Targeted degradation of transcription factor | TOI and Halo-tag fused dCAS9 |
| SNIPER (specific and non-genetic IAP-dependent protein erasers) | Proteasome | POI and IAP |
| KINETAC (cytokine receptor targeting chimeras) | Lysosome (membrane bound and cell-surface proteins) | POI and cytokine receptor |
| PROTAB (proteolysis targeting antibodies) | Proteasome (membrane bound and cell-surface proteins) | POI and Ab (cell surface ligase) |
| AUTOTAC/AUTAC (autophagy targeting chimera) | Lysosome | POI and autophagy receptor (ZZ domain) |
| GLUETAC | Covalent nanobody based PROTAC (cell-surface proteins) | POI and |
| PHOTAC (photochemically targeting chimeras) | Proteasome | POI, photoswitch and E3 |
