References TOPICREFERENCELINKERSUnraveling the Role of Linker Design in Proteolysis Targeting ChimerasLINKERSPROTACs bearing piperazine-containing linkers: what effect on their protonation state?ADMEUnderstanding the Metabolism of Proteolysis Targeting Chimeras (PROTACs): The Next Step toward Pharmaceutical ApplicationsADME, LINKERSDirect-to-Biology Accelerates PROTAC Synthesis and the Evaluation of Linker Effects on Permeability and DegradationADMEFundamental aspects of DMPK optimization of targeted protein degradersCOVALENTEfficient Targeted Degradation via Reversible and Irreversible Covalent PROTACsCOVALENTReversible Covalent PROTACs: Novel and Efficient Targeted Degradation StrategyDELOptimization of PROTAC Ternary Complex Using DNA Encoded Library ApproachPHOTOSWITCHESAzobenzene Photoswitches in Proteolysis Targeting Chimeras: Photochemical Control Strategies and Therapeutic BenefitsPROTAC SOLUBILITYDesigning Soluble PROTACs: Strategies and Preliminary GuidelinesPROTAC PRODRUGFirst orally bioavailable prodrug of proteolysis targeting chimera (PROTAC) degrades cyclin-dependent kinases 2/4/6 in vivoTUMOR TARGETINGFolate-Guided Protein Degradation by Immunomodulatory Imide Drug-Based Molecular Glues and Proteolysis Targeting Chimeras
